INSTITUTE FOR PHARMACEUTICAL SKILL DEVELOPMENT AND RESEARCH
A cornerstone platform for pharmaceutical research
WELCOME TO IPSDRLAB
A cornerstone platform for pharmaceutical research
Institute for Pharmaceutical Skill Development and Research (IPSDRLAB) is basically a private initiative to promote and make laboratory research accessible to all pharmacy students in the country. The lab provides platform for learning latest laboratory techniques through extensive training programs and opportunities for conducting projects on variety of subject areas including pharmacology, neuroscience, pharmaceutics, pharmaceutical technology, phytochemistry, pharmaceutical microbiology and so on. It intends to assist research enthusiasts to strengthen their foundation and allow them to prepare for their future endeavors.
RESEARCH & DISCOVERIES
INTEGRATED APPROACH TO STUDY NEUROBEHAVIOR
Depression followed by anxiety is the common phenomenological symptoms in neurobehavioral study, though rarely co-investigated within a particular experimental model. A range of test methods have been developed to evaluate these two neurological conditions separately but few approaches have been reported to understand the correlation. The major drawbacks in such study designs are the limit to challenge the same subject keeping the same physiological, psychological and surrounding environmental conditions for different experiments - the reason that drives the investigators to design the experiments individually with identical subjects. As a consequence, major gaps on relevancy in behavior are observed. Thus, our present study is aimed to minimize this gap by integrating three experimental designs in a cascade for utilizing the same subjects with their unique characteristics.
REJUVENATING WEAK ANTIBIOTICS AGAINST RESISTANT BACTERIA
As a consequence of bacterial resistance, previously useful antibiotics have lost their efficacy, and broader-spectrum antibiotics are being brought into action. As an inherent characteristic, bacteria tend to develop resistance toward applied antibiotics by mutation, which implies the great risk for destroying the last-line agents for controlling the infectious diseases. Once considered a miraculous drug, penicillin now found ineffective against almost all types of infections. Amoxiclav, a highly potent
combination drug, is being reported as ineffective in controlling diseases. We are trying to rejuvenate these weak antibiotics with the help of natural agents against resistant bacteria.
COMPARATIVE DISSOLUTION STUDY UNDER BIOWAIVER CONDITION
Biowaiver is an alternative technique to invivo pharmacokinetic bioequivalence studies approved by FDA. Dissolution performs a significant role in releasing drug substance from the drug product in the body for its subsequent absorption. It largely depends on the physicochemical properties of drugs as well as the formulation and process of manufacturing of the drug product. Hence, it is essential to undertake constant dissolution analysis of marketed drug products to assure the quality medicines. Our study is aimed to assess the pharmaceutical equivalence of marketed tablets using in vitro dissolution study under biowaiver condition.
ZEBRAFISH PHARMACOLOGY
Zebrafish possess all major neurotransmitters, hormones, and relevant receptors, and their neurotransmitter and neuroendocrine systems share several structural properties with mammalian systems. There is a high degree of genetic overlap between zebrafish and humans, with approximately 70% of human genes having at least one zebrafish orthologue. We are trying to understand the capabilities and limitations of zebrafish for disease modelling, drug screening, target identification, pharmacology, and toxicology.
PUBLISHED WORKS
2022
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Naim SMRQ, Nawrin K, Islam MN. Ketamine attenuates memory and motor impairment associated with Alzheimer’s disease. Pharmacotherapy and Pharmascience Discovery. 2022; 2(1):7-15. (PDF)
Naim SMRQ, Nawrin K, Islam MN. Lurasidone in the management of Ketamine overdose. Pharmacotherapy and Pharmascience Discovery. 2022; 2(1):1-6. (PDF)
Sarker J, Islam MN. Comparative summary of the ethnomedicinal use, phytochemical constituents, and pharmacological properties of Syzygium aromaticum and Ocimum sanctum. Pharmacotherapy and Pharmascience Discovery. 2021;1(2):82-100. (PDF)
2021
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Hossin A, Jabed MSU, Tushar RR, Nawrin K, Billah MM*. Central and peripheral antinociceptive activity of D. linearis ethanolic leaf extract. Pharmacotherapy and Pharmascience Discovery. 2021;1(2):74-81. (PDF)
Billah MM*, Nawrin K, Jabed MSU, Hossin A, Islam MN. Antitussive and expectorant activities of formulated leaf-root extract mixtures of Ocimum sanctum and their conjugation with standards. Pharmacotherapy and Pharmascience Discovery. 2021;1(2):65-73. (PDF)
Billah MM*, Hossin A, Nawrin K, Ahmed F. New insights into tau protein with regard to Alzheimer’s disease and other tauopathies. Pharmacotherapy and Pharmascience Discovery. 2021;1(2):55-64. (PDF)
Olive AH, Ahmed F, Billah MM*. Broad-spectrum antibacterial efficacy of neem oil-penicillin combination therapy against resistant bacteria. Pharmacotherapy and Pharmascience Discovery. 2021;1(2):46-54. (PDF)
Rashed SSB, Tushar RR, Ahmed F, Vabna NJ, Jahan L, Billah MM*. Comparative in vitro Dissolution Study of Clonazepam Tablets of Bangladesh by UV-Visible Spectrophotometry. Acta Pharm. Sci. 2021;59(4):641-653. (PDF)
Chowdhury AS, Mostaq MS, Halder N, Razu MAI, Billah MM*, Habib MR. Evaluation of antibacterial activity of mustard honey and its potential to boost the efficacy of penicillin and amoxiclav against resistant bacteria. Phol. 2021;2: 1365-1373. (PDF)
Iqbal A, Chowdhury AS*. Formulated honey benefits the action of penicillin and amoxiclav against resistant bacteria. Pharmacotherapy and Pharmascience Discovery. 2021;1(1):37-45. (PDF)
Hasan S, Ahmed F, Tushar RR, Jahan L, Hossen MA. In vitro assessment of pharmaceutical equivalence and analysis of drug release kinetics of Domperidone 10mg tablets available in Bangladesh market. Pharmacotherapy and Pharmascience Discovery. 2021;1(1):29-36. (PDF)
Billah MM*, Nawrin K, Rayhan MA, Ahmed F, Hossin A, Islam MN*. Honeys from diverse geographical sources supplement the action of penicillin and amoxiclav – a comparative antibacterial study. Pharmacotherapy and Pharmascience Discovery. 2021;1(1):19-28. (PDF)
Nawrin K*, Billah MM, Ahmed F, Hossin A, Tushar RR, Islam MN*. Protective potential of C. sinensis fruit peel aqueous extract on in vitro inflammation. Pharmacotherapy and Pharmascience Discovery. 2021;1(1):10-18. (PDF)
Rayhan MA, Vabna NJ, Ahmed F, Hossin A, Nawrin K, Billah MM*. Jujube (Ziziphus jujube) honey treats stress induced anxiety behavior in mice. Pharmacotherapy and Pharmascience Discovery. 2021;1(1):1-9. (PDF)
Billah MM, Chowdhury AS, Nawrin K, Mostaq S, Rayhan MA, Tushar RR. Serotonergic and noradrenergic response of ethanol extract; opioidergic response of ethyl acetate extract of Dicranopteris linearis L. leaf. Clin Phytosci. 2021; 7(25). (PDF)
2020
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Billah MM*, Huzaifa A, Khan MAK, Vabna NJ, Nawrin K, Rayhan MA. Suppression of inflammatory mediators by aqueous leaf extract of Crotalaria verrucosa: in vivo and in vitro analysis. Int J Basic Clin Pharmacol. 2020; 9(1): 897-902. (PDF)
Khan M, Islam Z, Chowdhury AS, Yousuf SA, Amin MR, Rayhan MA. Wild honey facilitates antibacterial efficacy of penicillin and amoxicillin–clavulanic acid. J Apither. 2020; 7(2): 22-30. (PDF)
Hossain R, Rahman MS, Rayhan MA, Nawrin K, Billah MM*, Habib MR. Antibacterial efficacy of black seed honey in combination with penicillin and amoxiclav against gram-positive bacteria. Int J Sci Rep 2020;6(2):61-6. (PDF)
2019
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Vabna NJ, Sultana N, Khan M, Ghosh B, Nawrin K, Billah MM*. Lychee Honey Accelerates Antibacterial Efficacy of Penicillin and Amoxiclav Against Gram-Positive Bacteria. Am J Biomed Sci & Res. 2019; 6(3):226-31. (PDF)
Billah MM*, Rayhan MA, Yousuf SA, Nawrin K, Rayhan J, Khengari EM. A Novel Integrated (OF-HC-EPM) Approach to Study Anxiety Related Depressive Behavior in Mice Model: A Comparison of Neuro Standards. Advances in Pharmacology and Pharmacy, 2019; 7(3): 39-48. (PDF)
Billah MM*, Rayhan MA, Yousuf SA, Nawrin K, Hossin A, Khengari EM. Integrated OF-HC-EPM approach to assess sedative-anxiolytic potential of honey derived from mustard (Brassica nigra) flower. Int J Sci Rep 2019; 5(8): 201-6. (PDF)
Rayhan A, Yousuf SA, Rayhan J, Khengari E, Nawrin K*, Billah MM. Black Seed Honey – A Powerful Ingredient of Prophetic Medicine; Its Neuropharmacological Potential. J Apither. 2019; 5(2): 18-26. (PDF)
Billah MM*, Rayhan MA, Yousuf SA, Nawrin K, Jabed M.S.U, Vabna N. A Novelty-Induced Integrated Environmental Challenge to Assess Neuropharmacological Potential of Lychee (Litchi chinenesis) Honey. American Journal of Biomedical Sciences, 2019; 11(3), 120-129. (PDF)
LAB MEMBERS
MOHAMMAD MUSTAKIM BILLAH
Founder;Â Investigator & Instructor
fpi@ipsdrlab.com
KASHFIA NAWRIN
Principal Scientific Officer
pso@ipsdrlab.com
DR. MD. NURULÂ ISLAM
Research Advisor, Pharmacology & Pharmaceutical Microbiology
mniadvisor@ipsdrlab.com
DR. ELMABRUK KHENGARI
Research Advisor, Clinical Studies
emkadvisor@ipsdrlab.com
RAZWANUR RAHMAN TUSHAR
Research Adviser, Pharmaceutical Technology
rrtadvisor@ipsdrlab.com
FAIRUZA AHMED
Research Coordinator (On Study Leave), Currently studying Biomedical Sciences at University of York, UK)
farc@ipsdrlab.com
S M RUHUL QUDUS NAIM
Lab Coordinator
NUSRAT JAHAN VABNA
Instructor, Scientific Writing
njvsw@ipsdrlab.com
ABU RAYHAN
Former Research Coordinator, Currently studying anticancer project at National Cancer Center, South Korea with a government fellowship.
AYREEN SONIAÂ CHOWDHURY
Former Research Apprentice, Currently studying Pharmacology at Nottingham Trent University, UK and an intern at University of Texas at El Paso, USA.
CURRENT MEMBERS
Mohammed Sahek Ullah Jabed, Arif Hossin, Jasica Sarker, Jannatul Ferdaus Alo, Rohona Chowdhury, Jafrin Alam Primon.
PAST MEMBERS
Abeer Hasan Olive, Khalid Saifullah, Samiha Binte Iqbal, Fazle Rabby, Mehnaz Sultana, Sadman Sakib Bin Rashed, Sirajum Munira, Tamanna Dipsha, Hassan Samira, Mahi Khan, Rozely Hossain , Asif Iqbal, Md. Ifta Khairul Alam Shopon, Md. Rony, Johir Rayhan, Abul Hossen, Laila Jahan, Mostaq Sumon, Nadia Sulatana, Zahirul Islam, Badol Ghosh, Md. Shamimur Rahman, Md. Abdul Qader Khan, Syed Ali Yousuf, Md. Ruhul Amin.
LATEST NEWS
NEUROINFLAMMATION RESEARCH
IPSDRLAB is developing protocols for studying the difference in signaling of neurotransmitters in inflammation.
PENICILLIN WORKS !
Wild honey not only possesses an inhibitory effect to resistant bacteria but also facilitates the action of Penicillin and Amoxiclav, thereby also generates a scope for research for
identifying new potential antibacterial agents.
ZEBRAFISH IN LIEU OF ANIMALS - MINIMIZING OUTBREAK RISKS IN PANDEMIC SITUATIONS
Animal models are the high risk factors for disease outbreaks specially during pandemics. As a result, scientists suffer from shutdown of labs. Alternatively, zebrafish can be a useful tool having minimal risk for such outbreaks and can facilitate the continuation of research.
CAREERS
Join IPSDRLAB
October 10, 2020
RESEARCH APPRENTICE
Positions (02) available for Research Apprentices (full-time).
*Fresh graduates in Pharmacy discipline
*Desire to learn laboratory project works
*Excellent writing skills in English
Interested candidates are requested to reach at ipsdrlab@gmail.com with their academic CVs.
Please feel free to ask your queries @01977666373.
Candidates will be selected through an assessment.
All apprenticeship jobs come with opportunities to participate in projects and author publications, however, are non-paid.
This call is valid till October 20, 2020 or until filled.
Available immediately.
COME WORK WITH US
Join the Team
IPSDRLAB always encourage enthusiastic researchers to join
